M45L (p.Met45Leu) variant of IL33 (Interleukin-33)
M45L (p.Met45Leu) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
M45L (p.Met45Leu) variant details
- p.Met45Leu
- gnomAD 9-6250515-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.39
- AlphaMissense 0.32
- MetaLR 0.11
- MetaSVM -0.95
- CADD 14.50
- PolyPhen-2 0.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available