M45K (p.Met45Lys) variant of IL33 (Interleukin-33)
M45K (p.Met45Lys) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
M45K (p.Met45Lys) variant details
- p.Met45Lys
- ExAC rs773578845
- gnomAD rs773578845
- Missense
- Variant Prioritization Score for Impact Estimate 0.28
- AlphaMissense 0.41
- MetaLR 0.13
- MetaSVM -0.92
- CADD 15.90
- PolyPhen-2 0.06
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available