M42V (p.Met42Val) variant of IL33 (Interleukin-33)
M42V (p.Met42Val) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
M42V (p.Met42Val) variant details
- p.Met42Val
- ExAC rs748625551
- TOPMed rs748625551
- gnomAD rs748625551
- Missense
- Variant Prioritization Score for Impact Estimate 0.146
- AlphaMissense 0.05
- MetaLR 0.04
- MetaSVM -0.99
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available