M42K (p.Met42Lys) variant of IL33 (Interleukin-33)
M42K (p.Met42Lys) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
M42K (p.Met42Lys) variant details
- p.Met42Lys
- gnomAD 9-6250507-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.141
- AlphaMissense 0.12
- MetaLR 0.09
- MetaSVM -1.02
- CADD 0.10
- PolyPhen-2 0.02
- SIFT 0.03
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available
- Literature evidence available