M42C (p.Met42Cys) variant of IL33 (Interleukin-33)
M42C (p.Met42Cys) in IL33 (Interleukin-33) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
M42C (p.Met42Cys) variant details
- p.Met42Cys
- rs758191115
- gnomAD 9-6250501-GC-G
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.458
- CADD 16.70
- Most common in the Non-Finnish European population (allele frequency 4.5e-06)
- Structural context available
- Literature evidence available