L47V (p.Leu47Val) variant of IL33 (Interleukin-33)
L47V (p.Leu47Val) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data, published literature, and structural context.
L47V (p.Leu47Val) variant details
- p.Leu47Val
- gnomAD 9-6250521-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.442
- AlphaMissense 0.33
- MetaLR 0.28
- MetaSVM -0.82
- CADD 23.10
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available