L29M (p.Leu29Met) variant of IL33 (Interleukin-33)
L29M (p.Leu29Met) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
L29M (p.Leu29Met) variant details
- p.Leu29Met
- TOPMed rs1161011437
- Missense
- Variant Prioritization Score for Impact Estimate 0.243
- AlphaMissense 0.11
- MetaLR 0.20
- MetaSVM -0.87
- CADD 13.80
- PolyPhen-2 0.97
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available