K66R (p.Lys66Arg) variant of IL33 (Interleukin-33)
K66R (p.Lys66Arg) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
K66R (p.Lys66Arg) variant details
- p.Lys66Arg
- gnomAD rs1340940380
- Missense
- Variant Prioritization Score for Impact Estimate 0.319
- AlphaMissense 0.08
- MetaLR 0.11
- MetaSVM -1.01
- CADD 10.80
- PolyPhen-2 0.21
- SIFT 0.09
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available