K54T (p.Lys54Thr) variant of IL33 (Interleukin-33)
K54T (p.Lys54Thr) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
K54T (p.Lys54Thr) variant details
- p.Lys54Thr
- ExAC rs751415058
- TOPMed rs751415058
- gnomAD rs751415058
- Missense
- Variant Prioritization Score for Impact Estimate 0.275
- AlphaMissense 0.20
- MetaLR 0.08
- MetaSVM -1.02
- CADD 15.90
- PolyPhen-2 0.72
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available