K54R (p.Lys54Arg) variant of IL33 (Interleukin-33)
K54R (p.Lys54Arg) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
K54R (p.Lys54Arg) variant details
- p.Lys54Arg
- ExAC rs751415058
- TOPMed rs751415058
- gnomAD rs751415058
- Missense
- Variant Prioritization Score for Impact Estimate 0.23
- AlphaMissense 0.09
- MetaLR 0.05
- MetaSVM -1.04
- CADD 8.57
- PolyPhen-2 0.02
- SIFT 0.65
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available