K35R (p.Lys35Arg) variant of IL33 (Interleukin-33)
K35R (p.Lys35Arg) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data and structural context.
K35R (p.Lys35Arg) variant details
- p.Lys35Arg
- Ensembl rs2130418759
- Missense
- Variant Prioritization Score for Impact Estimate 0.544
- AlphaMissense 0.11
- MetaLR 0.22
- MetaSVM -0.92
- CADD 23.50
- PolyPhen-2 0.98
- SIFT 0.03
- Most common in the HGDP:ADYGEI population (allele frequency 0.029)
- Structural context available