K35N (p.Lys35Asn) variant of IL33 (Interleukin-33)
K35N (p.Lys35Asn) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
K35N (p.Lys35Asn) variant details
- p.Lys35Asn
- gnomAD rs1431416448
- Missense
- Variant Prioritization Score for Impact Estimate 0.206
- AlphaMissense 0.26
- MetaLR 0.17
- MetaSVM -0.92
- CADD 7.75
- PolyPhen-2 0.74
- SIFT 0.01
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available