K31N (p.Lys31Asn) variant of IL33 (Interleukin-33)
K31N (p.Lys31Asn) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data and structural context.
K31N (p.Lys31Asn) variant details
- p.Lys31Asn
- gnomAD rs1816283684
- Missense
- Variant Prioritization Score for Impact Estimate 0.544
- AlphaMissense 0.22
- MetaLR 0.22
- MetaSVM -0.93
- CADD 22.90
- PolyPhen-2 0.99
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available