K31E (p.Lys31Glu) variant of IL33 (Interleukin-33)
K31E (p.Lys31Glu) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
K31E (p.Lys31Glu) variant details
- p.Lys31Glu
- 1000Genomes rs533535426
- ExAC rs533535426
- TOPMed rs533535426
- gnomAD rs533535426
- Missense
- Variant Prioritization Score for Impact Estimate 0.287
- AlphaMissense 0.11
- MetaLR 0.04
- MetaSVM -0.96
- CADD 15.30
- PolyPhen-2 0.32
- SIFT 0.17
- Most common in the 1KG:PUR population (allele frequency 0.0051)
- Structural context available