K2N (p.Lys2Asn) variant of IL33 (Interleukin-33)
K2N (p.Lys2Asn) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
K2N (p.Lys2Asn) variant details
- p.Lys2Asn
- TOPMed rs1422033408
- gnomAD rs1422033408
- Missense
- Variant Prioritization Score for Impact Estimate 0.449
- AlphaMissense 0.39
- MetaLR 0.24
- MetaSVM -0.91
- CADD 22.70
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available