K28R (p.Lys28Arg) variant of IL33 (Interleukin-33)
K28R (p.Lys28Arg) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
K28R (p.Lys28Arg) variant details
- p.Lys28Arg
- gnomAD 9-6241777-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.314
- AlphaMissense 0.10
- MetaLR 0.14
- MetaSVM -0.95
- CADD 13.00
- PolyPhen-2 0.70
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available