K28Q (p.Lys28Gln) variant of IL33 (Interleukin-33)
K28Q (p.Lys28Gln) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data and structural context.
K28Q (p.Lys28Gln) variant details
- p.Lys28Gln
- ExAC rs753806663
- TOPMed rs753806663
- gnomAD rs753806663
- Missense
- Variant Prioritization Score for Impact Estimate 0.616
- AlphaMissense 0.15
- MetaLR 0.30
- MetaSVM -0.74
- CADD 21.60
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available