K23R (p.Lys23Arg) variant of IL33 (Interleukin-33)
K23R (p.Lys23Arg) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data, published literature, and structural context.
K23R (p.Lys23Arg) variant details
- p.Lys23Arg
- gnomAD 9-6241762-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.44
- AlphaMissense 0.09
- MetaLR 0.09
- MetaSVM -1.03
- CADD 8.83
- PolyPhen-2 0.46
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available