K11E (p.Lys11Glu) variant of IL33 (Interleukin-33)
K11E (p.Lys11Glu) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
K11E (p.Lys11Glu) variant details
- p.Lys11Glu
- cosmic curated COSV67343
- TOPMed rs1819539160
- Missense
- Variant Prioritization Score for Impact Estimate 0.342
- AlphaMissense 0.12
- MetaLR 0.11
- MetaSVM -0.98
- CADD 17.60
- PolyPhen-2 0.04
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 6.3e-06)
- Structural context available