I53T (p.Ile53Thr) variant of IL33 (Interleukin-33)
I53T (p.Ile53Thr) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
I53T (p.Ile53Thr) variant details
- p.Ile53Thr
- gnomAD rs1816290100
- Missense
- Variant Prioritization Score for Impact Estimate 0.387
- AlphaMissense 0.50
- MetaLR 0.17
- MetaSVM -0.91
- CADD 21.60
- PolyPhen-2 0.87
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available