I12T (p.Ile12Thr) variant of IL33 (Interleukin-33)
I12T (p.Ile12Thr) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
I12T (p.Ile12Thr) variant details
- p.Ile12Thr
- gnomAD 9-6241729-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.256
- AlphaMissense 0.18
- MetaLR 0.10
- MetaSVM -1.00
- CADD 7.01
- PolyPhen-2 0.09
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available