G50D (p.Gly50Asp) variant of IL33 (Interleukin-33)
G50D (p.Gly50Asp) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data, published literature, and structural context.
G50D (p.Gly50Asp) variant details
- p.Gly50Asp
- gnomAD 9-6250531-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.476
- AlphaMissense 0.57
- MetaLR 0.35
- MetaSVM -0.67
- CADD 23.40
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available