G50C (p.Gly50Cys) variant of IL33 (Interleukin-33)
G50C (p.Gly50Cys) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data, published literature, and structural context.
G50C (p.Gly50Cys) variant details
- p.Gly50Cys
- gnomAD 9-6250530-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.473
- AlphaMissense 0.51
- MetaLR 0.34
- MetaSVM -0.72
- CADD 24.10
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available
- Literature evidence available