G50A (p.Gly50Ala) variant of IL33 (Interleukin-33)
G50A (p.Gly50Ala) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
G50A (p.Gly50Ala) variant details
- p.Gly50Ala
- gnomAD rs1816289184
- Missense
- Variant Prioritization Score for Impact Estimate 0.476
- AlphaMissense 0.44
- MetaLR 0.35
- MetaSVM -0.67
- CADD 23.20
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available