F60S (p.Phe60Ser) variant of IL33 (Interleukin-33)
F60S (p.Phe60Ser) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
F60S (p.Phe60Ser) variant details
- p.Phe60Ser
- gnomAD 9-6250561-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.354
- AlphaMissense 0.23
- MetaLR 0.30
- MetaSVM -0.72
- CADD 22.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available
- Literature evidence available