F60L (p.Phe60Leu) variant of IL33 (Interleukin-33)
F60L (p.Phe60Leu) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
F60L (p.Phe60Leu) variant details
- p.Phe60Leu
- ExAC rs748626570
- TOPMed rs748626570
- gnomAD rs748626570
- Missense
- Variant Prioritization Score for Impact Estimate 0.278
- AlphaMissense 0.64
- MetaLR 0.23
- MetaSVM -0.87
- CADD 20.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 0.00011)
- Structural context available