F60C (p.Phe60Cys) variant of IL33 (Interleukin-33)
F60C (p.Phe60Cys) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
F60C (p.Phe60Cys) variant details
- p.Phe60Cys
- gnomAD rs1387802000
- Missense
- Variant Prioritization Score for Impact Estimate 0.353
- AlphaMissense 0.20
- MetaLR 0.30
- MetaSVM -0.69
- CADD 22.80
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available