E56K (p.Glu56Lys) variant of IL33 (Interleukin-33)
E56K (p.Glu56Lys) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
E56K (p.Glu56Lys) variant details
- p.Glu56Lys
- gnomAD 9-6250548-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.344
- AlphaMissense 0.10
- MetaLR 0.05
- MetaSVM -1.03
- CADD 0.82
- PolyPhen-2 0.00
- SIFT 0.67
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available
- Literature evidence available