E38D (p.Glu38Asp) variant of IL33 (Interleukin-33)
E38D (p.Glu38Asp) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
E38D (p.Glu38Asp) variant details
- p.Glu38Asp
- gnomAD 9-6250496-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.421
- AlphaMissense 0.13
- MetaLR 0.11
- MetaSVM -0.99
- CADD 12.60
- PolyPhen-2 0.09
- SIFT 0.08
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available