C58Y (p.Cys58Tyr) variant of IL33 (Interleukin-33)
C58Y (p.Cys58Tyr) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
C58Y (p.Cys58Tyr) variant details
- p.Cys58Tyr
- gnomAD 9-6250555-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.175
- AlphaMissense 0.18
- MetaLR 0.09
- MetaSVM -0.99
- CADD 6.98
- PolyPhen-2 0.01
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available
- Literature evidence available