C58S (p.Cys58Ser) variant of IL33 (Interleukin-33)
C58S (p.Cys58Ser) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
C58S (p.Cys58Ser) variant details
- p.Cys58Ser
- gnomAD 9-6250555-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.167
- AlphaMissense 0.20
- MetaLR 0.05
- MetaSVM -1.06
- CADD 6.49
- PolyPhen-2 0.00
- SIFT 0.20
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available