C58L (p.Cys58Leu) variant of IL33 (Interleukin-33)
C58L (p.Cys58Leu) in IL33 (Interleukin-33) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
C58L (p.Cys58Leu) variant details
- p.Cys58Leu
- rs1169854342
- gnomAD 9-6250551-G-GC
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.224
- CADD 20.20
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available