C58G (p.Cys58Gly) variant of IL33 (Interleukin-33)
C58G (p.Cys58Gly) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
C58G (p.Cys58Gly) variant details
- p.Cys58Gly
- ExAC rs779013655
- gnomAD rs779013655
- Missense
- Variant Prioritization Score for Impact Estimate 0.326
- AlphaMissense 0.13
- MetaLR 0.11
- MetaSVM -0.97
- CADD 18.60
- PolyPhen-2 0.16
- SIFT 0.02
- Most common in the South Asian population (allele frequency 3.5e-05)
- Structural context available