C58F (p.Cys58Phe) variant of IL33 (Interleukin-33)
C58F (p.Cys58Phe) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
C58F (p.Cys58Phe) variant details
- p.Cys58Phe
- gnomAD rs1306183928
- Missense
- Variant Prioritization Score for Impact Estimate 0.215
- AlphaMissense 0.17
- MetaLR 0.10
- MetaSVM -1.00
- CADD 13.70
- PolyPhen-2 0.40
- SIFT 0.00
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available