C40S (p.Cys40Ser) variant of IL33 (Interleukin-33)
C40S (p.Cys40Ser) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
C40S (p.Cys40Ser) variant details
- p.Cys40Ser
- 1000Genomes rs185775049
- gnomAD rs185775049
- Missense
- Variant Prioritization Score for Impact Estimate 0.39
- AlphaMissense 0.27
- MetaLR 0.16
- MetaSVM -0.89
- CADD 12.00
- PolyPhen-2 0.58
- SIFT 0.00
- Most common in the 1KG:ASW population (allele frequency 0.0098)
- Structural context available