A57S (p.Ala57Ser) variant of IL33 (Interleukin-33)
A57S (p.Ala57Ser) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
A57S (p.Ala57Ser) variant details
- p.Ala57Ser
- 1000Genomes rs183839589
- TOPMed rs183839589
- gnomAD rs183839589
- Missense
- Variant Prioritization Score for Impact Estimate 0.169
- AlphaMissense 0.12
- MetaLR 0.07
- MetaSVM -1.06
- CADD 4.60
- PolyPhen-2 0.19
- SIFT 0.10
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available