A24D (p.Ala24Asp) variant of IL33 (Interleukin-33)
A24D (p.Ala24Asp) in IL33 (Interleukin-33) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
A24D (p.Ala24Asp) variant details
- p.Ala24Asp
- ExAC rs767146393
- TOPMed rs767146393
- gnomAD rs767146393
- Missense
- Variant Prioritization Score for Impact Estimate 0.565
- AlphaMissense 0.23
- MetaLR 0.19
- MetaSVM -0.91
- CADD 16.60
- PolyPhen-2 0.93
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 6.6e-05)
- Structural context available