W30G (p.Trp30Gly) variant of IL23A (Interleukin-23 subunit alpha)
W30G (p.Trp30Gly) in IL23A (Interleukin-23 subunit alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data, published literature, and structural context.
W30G (p.Trp30Gly) variant details
- p.Trp30Gly
- gnomAD 12-56339132-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.49
- REVEL 0.45
- MetaLR 0.18
- MetaSVM -0.76
- CADD 26.70
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- Literature evidence available