S4R (p.Ser4Arg) variant of IL23A (Interleukin-23 subunit alpha)
S4R (p.Ser4Arg) in IL23A (Interleukin-23 subunit alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
S4R (p.Ser4Arg) variant details
- p.Ser4Arg
- gnomAD 12-56339056-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.142
- REVEL 0.04
- MetaLR 0.14
- MetaSVM -0.98
- CADD 12.60
- PolyPhen-2 0.03
- SIFT 0.07
- Population evidence available
- Structural context available
- Literature evidence available