S27R (p.Ser27Arg) variant of IL23A (Interleukin-23 subunit alpha)
S27R (p.Ser27Arg) in IL23A (Interleukin-23 subunit alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
S27R (p.Ser27Arg) variant details
- p.Ser27Arg
- gnomAD 12-56339125-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.229
- REVEL 0.10
- MetaLR 0.05
- MetaSVM -0.98
- CADD 17.40
- PolyPhen-2 0.16
- SIFT 0.19
- Population evidence available
- Structural context available
- Literature evidence available