S27I (p.Ser27Ile) variant of IL23A (Interleukin-23 subunit alpha)
S27I (p.Ser27Ile) in IL23A (Interleukin-23 subunit alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
S27I (p.Ser27Ile) variant details
- p.Ser27Ile
- gnomAD 12-56339124-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.214
- REVEL 0.09
- MetaLR 0.07
- MetaSVM -0.97
- CADD 21.80
- PolyPhen-2 0.36
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- Literature evidence available