S27G (p.Ser27Gly) variant of IL23A (Interleukin-23 subunit alpha)
S27G (p.Ser27Gly) in IL23A (Interleukin-23 subunit alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
S27G (p.Ser27Gly) variant details
- p.Ser27Gly
- ExAC rs202124814
- gnomAD rs202124814
- Missense
- Variant Prioritization Score for Impact Estimate 0.118
- REVEL 0.03
- MetaLR 0.06
- MetaSVM -1.04
- CADD 17.90
- PolyPhen-2 0.00
- SIFT 0.35
- Most common in the South Asian population (allele frequency 7.2e-05)
- Structural context available