Q38H (p.Gln38His) variant of IL23A (Interleukin-23 subunit alpha)
Q38H (p.Gln38His) in IL23A (Interleukin-23 subunit alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
Q38H (p.Gln38His) variant details
- p.Gln38His
- gnomAD 12-56339158-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.262
- REVEL 0.12
- MetaLR 0.08
- MetaSVM -0.85
- CADD 24.10
- PolyPhen-2 0.45
- SIFT 0.01
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available