Q35R (p.Gln35Arg) variant of IL23A (Interleukin-23 subunit alpha)
Q35R (p.Gln35Arg) in IL23A (Interleukin-23 subunit alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
Q35R (p.Gln35Arg) variant details
- p.Gln35Arg
- ESP rs370833575
- ExAC rs370833575
- TOPMed rs370833575
- gnomAD rs370833575
- Missense
- Variant Prioritization Score for Impact Estimate 0.22
- REVEL 0.14
- MetaLR 0.09
- MetaSVM -0.98
- CADD 17.90
- PolyPhen-2 0.04
- SIFT 0.38
- Most common in the REMAINING population (allele frequency 5.1e-05)
- Structural context available