Q32K (p.Gln32Lys) variant of IL23A (Interleukin-23 subunit alpha)
Q32K (p.Gln32Lys) in IL23A (Interleukin-23 subunit alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
Q32K (p.Gln32Lys) variant details
- p.Gln32Lys
- gnomAD 12-56339138-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.276
- REVEL 0.10
- MetaLR 0.09
- MetaSVM -1.04
- CADD 9.90
- PolyPhen-2 0.00
- SIFT 0.93
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- Literature evidence available