P23S (p.Pro23Ser) variant of IL23A (Interleukin-23 subunit alpha)
P23S (p.Pro23Ser) in IL23A (Interleukin-23 subunit alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
P23S (p.Pro23Ser) variant details
- p.Pro23Ser
- TOPMed rs1305275384
- gnomAD rs1305275384
- Missense
- Variant Prioritization Score for Impact Estimate 0.12
- REVEL 0.02
- MetaLR 0.04
- MetaSVM -1.05
- CADD 11.90
- PolyPhen-2 0.00
- SIFT 0.14
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available