P14T (p.Pro14Thr) variant of IL23A (Interleukin-23 subunit alpha)
P14T (p.Pro14Thr) in IL23A (Interleukin-23 subunit alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
P14T (p.Pro14Thr) variant details
- p.Pro14Thr
- ExAC rs774022773
- gnomAD rs774022773
- Missense
- Variant Prioritization Score for Impact Estimate 0.182
- REVEL 0.05
- MetaLR 0.08
- MetaSVM -0.98
- CADD 0.94
- PolyPhen-2 0.00
- SIFT 0.20
- Most common in the East Asian population (allele frequency 0.00044)
- Structural context available