P14L (p.Pro14Leu) variant of IL23A (Interleukin-23 subunit alpha)
P14L (p.Pro14Leu) in IL23A (Interleukin-23 subunit alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
P14L (p.Pro14Leu) variant details
- p.Pro14Leu
- 1000Genomes rs145233794
- ESP rs145233794
- ExAC rs145233794
- TOPMed rs145233794
- Missense
- Variant Prioritization Score for Impact Estimate 0.147
- REVEL 0.07
- MetaLR 0.09
- MetaSVM -0.96
- CADD 7.12
- PolyPhen-2 0.00
- SIFT 0.29
- Most common in the 1KG:PJL population (allele frequency 0.0052)
- Structural context available