M8L (p.Met8Leu) variant of IL23A (Interleukin-23 subunit alpha)
M8L (p.Met8Leu) in IL23A (Interleukin-23 subunit alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data, published literature, and structural context.
M8L (p.Met8Leu) variant details
- p.Met8Leu
- gnomAD 12-56339066-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.109
- REVEL 0.10
- MetaLR 0.03
- MetaSVM -1.03
- CADD 0.05
- PolyPhen-2 0.00
- SIFT 0.99
- Population evidence available
- Structural context available
- Literature evidence available