L43M (p.Leu43Met) variant of IL23A (Interleukin-23 subunit alpha)
L43M (p.Leu43Met) in IL23A (Interleukin-23 subunit alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
L43M (p.Leu43Met) variant details
- p.Leu43Met
- gnomAD 12-56339171-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.275
- REVEL 0.23
- MetaLR 0.16
- MetaSVM -0.67
- CADD 22.90
- PolyPhen-2 0.99
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available